Geodon (Ziprasidone Hcl)

Geodon Review

Geodon is used to treat severe mental disorders like schizophrenia, which are characterized by distorted thoughts, perceptions, and emotions. Geodon helps manage schizophrenia's "positive symptoms," (visual and auditory hallucinations, and delusions) and may also help in treating the "negative symptoms" of schizophrenia (social withdrawal, apathy, lack of motivation, and an inability to experience pleasure). Geodon is also used to treat acute bipolar mania, including manic and mixed episodes.

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Geodon Drug Class and Mechanism

Ziprasidone is an oral and injectable drug that is used for treating psychoses, for example, schizophrenia. Although the mechanism of action of ziprasidone is not known, like other anti-psychotics, it inhibits communication between nerves of the brain. It does this by blocking receptors on the nerves for several neurotransmitters, the chemicals that nerves use to communicate with each other. It is thought that the beneficial effect of ziprasidone is due to its blocking of dopamine and serotonin receptors. It also inhibits the re-uptake of serotonin and norepinephrine by nerves in the brain like some anti-depressant drugs. Ziprasidone is associated with little or no weight gain, a feature that distinguishes it from other anti-psychotic drugs. Similarly, ziprasidone is unique among anti-psychotic drugs in that it does not increase cholesterol levels.

Geodon Uses

Geodon usually is taken twice a day. The usual starting dose is 20 mg twice daily. The dose may be increased over time to achieve the desired effect. Geodon should be taken with food (for example, shortly after a meal) since when taken on an empty stomach, much less geodon is absorbed.

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Geodon Side Effects

Drowsiness, dizziness, nausea, or constipation may occur. If these effects persist or worsen, notify your doctor or pharmacist promptly. Tell your doctor immediately if any of these unlikely but serious side effects occur: muscle stiffness, muscle spasms or twitching, weight gain, unusual increase or decrease in amount of urine, unusual increase in thirst, change in vision. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: fainting, irregular or unusually fast heartbeat (especially with fever and increased sweating), seizures, trouble swallowing, uncontrolled movements (especially of the face or tongue). Males: In the unlikely event you experience a painful or prolonged erection, seek immediate medical attention as this is considered a medical emergency. This medication may in rare instances increase your blood level of a certain hormone (prolactin). In females, this rare increase in prolactin levels may result in unwanted breast milk production, stopping of your menstrual period, or difficulty in becoming pregnant. In males, this rare effect may result in decreased sexual ability, inability to produce sperm, or enlarged breasts. If you develop any of these symptoms, tell your doctor immediately. A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Geodon Pregnancy

Ziprasidone has not been studied in pregnant women, but studies in animals have shown that ziprasidone causes birth defects. Nevertheless, a physician may chose to use ziprasidone if he/she feels that its benefits outweigh this potential concern.

Geodon Overdose

In case of acute overdosage, establish and maintain an airway and ensure adequate oxygenation and ventilation. Intravenous access should be established and gastric lavage (after intubation, if patient is unconscious) and administration of activated charcoal together with a laxative should be considered. The possibility of obtundation, seizure, or dystonic reaction of the head and neck following overdose may create a risk of aspiration with induced emesis. Cardiovascular monitoring should commence immediately and should include continuous electrocardiographic monitoring to detect possible arrhythmias. If antiarrhythmic therapy is administered, disopyramide, procainamide, and quinidine carry a theoretical hazard of additive QT-prolonging effects that might be additive to those of ziprasidone. Hypotension and circulatory collapse should be treated with appropriate measures such as intravenous fluids. If sympathomimetic agents are used for vascular support, epinephrine and dopamine should not be used, since beta stimulation combined with ?1 antagonism associated with ziprasidone may worsen hypotension. Similarly, it is reasonable to expect that the alpha-adrenergic-blocking properties of bretylium might be additive to those of ziprasidone, resulting in problematic hypotension.

Geodon More Information

Do not share this medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions. Keep this medicine out of the reach of children. If using this medicine for an extended period of time, obtain refills before your supply runs out.